Psoriatic Arthritis: Skin and Joint Disease

Psoriatic arthritis is a chronic inflammatory arthritis that develops in approximately thirty percent of individuals with psoriasis, the common immune-mediated skin condition characterized by the accelerated turnover and impaired differentiation of keratinocytes that produces the well-recognized raised, red, scaly plaques of psoriatic skin disease. The coexistence of inflammatory arthritis with a characteristic skin condition might […]

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Rheumatoid Arthritis: Autoimmune Joint Disease

Rheumatoid arthritis is a systemic autoimmune disease whose most clinically prominent manifestation is persistent, symmetric inflammation of the synovial joints of the hands, wrists, feet, and larger joints, but whose disease process extends far beyond the joints to produce systemic inflammation with consequences for the cardiovascular system, lungs, bones, and neurological function that contribute substantially […]

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Osteoarthritis: Cartilage Breakdown and Management

Osteoarthritis is the most prevalent joint disease in the world and the leading musculoskeletal cause of disability in older adults, affecting an estimated five hundred million people globally and representing one of the most significant contributors to pain, functional limitation, and reduced quality of life across all demographic groups. For much of its clinical history, […]

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