Among the diverse precipitating factors that can trigger migraine attacks in susceptible individuals, psychological stress and environmental stimuli occupy a unique position as both the most universally recognized triggers by migraine patients themselves and among the most complex in their neurobiological relationship to migraine pathophysiology. Patient surveys consistently identify stress as the most frequently reported […]
The dramatic sex difference in migraine prevalence, with women being approximately three times more likely than men to suffer from migraine across the productive adult years, is one of the most striking epidemiological features of the condition and points unequivocally to the central role that female sex hormones play in modulating migraine susceptibility, attack frequency, […]
Migraine is one of the most prevalent and most disabling neurological disorders in the world, affecting approximately fifteen percent of the global adult population and ranking as the second leading cause of years lived with disability across all age groups in the Global Burden of Disease study. The condition is defined by recurrent episodes of […]